Transglycosylation method and protein having transglycosylation activity

The present invention provides a transglycosylation method and a protein catalyzing a transglycosylation reaction. A reaction of transferring a galactosylbeta1->3N-acetylgalactosaminyl group from a sugar donor containing a sugar chain having a galactosylbeta1->3N-acetylgalactosaminyl group bou...

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Bibliographische Detailangaben
Hauptverfasser: NAGAMINE NORIKO, YAMAMOTO KENJI, KATAYAMA TAKANE, KUMAGAI HIDEHIKO, OURA FUSAKO, FUJITA KIYOTAKA
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides a transglycosylation method and a protein catalyzing a transglycosylation reaction. A reaction of transferring a galactosylbeta1->3N-acetylgalactosaminyl group from a sugar donor containing a sugar chain having a galactosylbeta1->3N-acetylgalactosaminyl group bound thereto at the alpha-position, to a sugar chain acceptor, is carried out in the presence of a protein having an endo-alpha-N-acetylgalactosaminidase activity and a transglycosylation activity.