Pyrrolopyrimidine derivatives useful in cancer treatment

The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug, solvate or hydrate thereof, wherein L, R1, R2 R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treatin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LAGRECA SUSAN, CHEN JINSHAN, MARX MATTHEW A
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to compounds of the formula 1 or a pharmaceutically acceptable salt, prodrug, solvate or hydrate thereof, wherein L, R1, R2 R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating abnormal cell growth, such as cancer in a mammal by administering the compounds of formula 1.