Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation

The present invention provides apparatus, kits and methods for evaluating binding between one or more binding molecules (e.g., a protein) and one or more ligands. The invention also provides apparatus, kits and methods for detecting and/or quantifying a binding molecule, for example, a protein. Also...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	ST. CLAIRE ROBERT LEE III
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS SEPARATION SPIRITS TESTING TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides apparatus, kits and methods for evaluating binding between one or more binding molecules (e.g., a protein) and one or more ligands. The invention also provides apparatus, kits and methods for detecting and/or quantifying a binding molecule, for example, a protein. Also provided are apparatus, kits and methods for "stripping" a complex biological matrix of low molecular weight components. The invention can be carried out on a smaller process scale, and therefore be more efficient, than previously known methods. The present invention is particularly suitable for use in high-throughput assays, which can be partially or completely automated.