Novel tricyclic compounds and related methods of treatment

The invention provides novel lipid soluble forms of tricyclic antineoplastic compounds. These forms include salts, co-crystals, and solvates of the tricyclic antineoplastic compounds. The invention also provides novel pharmaceutical compositions comprising these novel lipid soluble forms and related...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MORISSETTE SHERRY, READ MICHAEL
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides novel lipid soluble forms of tricyclic antineoplastic compounds. These forms include salts, co-crystals, and solvates of the tricyclic antineoplastic compounds. The invention also provides novel pharmaceutical compositions comprising these novel lipid soluble forms and related methods of treatment. Compositions and methods of the invention are useful in the treatment of neoplasms, including MRP-1-related resistant neoplasms.