Compositions as adjuvants to improve immune responses to vaccines and methods of use

The invention provides compositions containing an antigen and a TIM targeting molecule. The invention additionally provides a TIM targeting molecule conjugate, for example, a TIM targeting molecule targeted to a therapeutic or diagnostic moiety. The invention additionally provides methods of using s...

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Bibliographische Detailangaben
Hauptverfasser:	HOO WILLIAM S, THATTE JAYANT, JENSEN ERIC R, YEI SOONPIN, MOLL THOMAS, CARLO DENNIS J, HELMICH BRIAN K
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention provides compositions containing an antigen and a TIM targeting molecule. The invention additionally provides a TIM targeting molecule conjugate, for example, a TIM targeting molecule targeted to a therapeutic or diagnostic moiety. The invention additionally provides methods of using such compositions. In one embodiment, the invention provides a method of stimulating an immune response in an individual by administering a composition comprising an antigen and a TIM targeting molecule in a pharmaceutically acceptable carrier. In another embodiment, the invention provides a method of stimulating an immune response in an individual by administering an antigen and a TIM targeting molecule, which can be administered together in a single composition or separately.