Ansamycins having improved pharmacological and biological properties
Ansamycins and methods of preparing and using the same are described. At least some of these ansamycins exhibit one or more of improved aqueous formulation ability, chemical stability, and bioavailability. Some of the derivatives described are dimers. These and others described can include one or mo...
Gespeichert in:
Hauptverfasser: | , , , , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | BURROWS FRANCIS J FRITZ LAWRENCE C LE BRAZIDEC JEAN-YVES BOEHM MARCUS F MCHUGH SEAN K ZHANG LIN FAN JUNHUA |
description | Ansamycins and methods of preparing and using the same are described. At least some of these ansamycins exhibit one or more of improved aqueous formulation ability, chemical stability, and bioavailability. Some of the derivatives described are dimers. These and others described can include one or more solubilizing groups that have expected merit in rendering the overall compounds useful as drugs and prodrugs. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2005267122A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2005267122A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2005267122A13</originalsourceid><addsrcrecordid>eNrjZHBxzCtOzK1MzswrVshILMvMS1fIzC0oyi9LTVEoyEgsyk1Mzs_JT89MTsxRSMxLUUjKhHOBqgpSi0oyU4t5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8aLCRgYGpkZm5oZGRo6ExcaoA5oQ0iQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Ansamycins having improved pharmacological and biological properties</title><source>esp@cenet</source><creator>BURROWS FRANCIS J ; FRITZ LAWRENCE C ; LE BRAZIDEC JEAN-YVES ; BOEHM MARCUS F ; MCHUGH SEAN K ; ZHANG LIN ; FAN JUNHUA</creator><creatorcontrib>BURROWS FRANCIS J ; FRITZ LAWRENCE C ; LE BRAZIDEC JEAN-YVES ; BOEHM MARCUS F ; MCHUGH SEAN K ; ZHANG LIN ; FAN JUNHUA</creatorcontrib><description>Ansamycins and methods of preparing and using the same are described. At least some of these ansamycins exhibit one or more of improved aqueous formulation ability, chemical stability, and bioavailability. Some of the derivatives described are dimers. These and others described can include one or more solubilizing groups that have expected merit in rendering the overall compounds useful as drugs and prodrugs.</description><edition>7</edition><language>eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20051201&DB=EPODOC&CC=US&NR=2005267122A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20051201&DB=EPODOC&CC=US&NR=2005267122A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BURROWS FRANCIS J</creatorcontrib><creatorcontrib>FRITZ LAWRENCE C</creatorcontrib><creatorcontrib>LE BRAZIDEC JEAN-YVES</creatorcontrib><creatorcontrib>BOEHM MARCUS F</creatorcontrib><creatorcontrib>MCHUGH SEAN K</creatorcontrib><creatorcontrib>ZHANG LIN</creatorcontrib><creatorcontrib>FAN JUNHUA</creatorcontrib><title>Ansamycins having improved pharmacological and biological properties</title><description>Ansamycins and methods of preparing and using the same are described. At least some of these ansamycins exhibit one or more of improved aqueous formulation ability, chemical stability, and bioavailability. Some of the derivatives described are dimers. These and others described can include one or more solubilizing groups that have expected merit in rendering the overall compounds useful as drugs and prodrugs.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBxzCtOzK1MzswrVshILMvMS1fIzC0oyi9LTVEoyEgsyk1Mzs_JT89MTsxRSMxLUUjKhHOBqgpSi0oyU4t5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8aLCRgYGpkZm5oZGRo6ExcaoA5oQ0iQ</recordid><startdate>20051201</startdate><enddate>20051201</enddate><creator>BURROWS FRANCIS J</creator><creator>FRITZ LAWRENCE C</creator><creator>LE BRAZIDEC JEAN-YVES</creator><creator>BOEHM MARCUS F</creator><creator>MCHUGH SEAN K</creator><creator>ZHANG LIN</creator><creator>FAN JUNHUA</creator><scope>EVB</scope></search><sort><creationdate>20051201</creationdate><title>Ansamycins having improved pharmacological and biological properties</title><author>BURROWS FRANCIS J ; FRITZ LAWRENCE C ; LE BRAZIDEC JEAN-YVES ; BOEHM MARCUS F ; MCHUGH SEAN K ; ZHANG LIN ; FAN JUNHUA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2005267122A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2005</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BURROWS FRANCIS J</creatorcontrib><creatorcontrib>FRITZ LAWRENCE C</creatorcontrib><creatorcontrib>LE BRAZIDEC JEAN-YVES</creatorcontrib><creatorcontrib>BOEHM MARCUS F</creatorcontrib><creatorcontrib>MCHUGH SEAN K</creatorcontrib><creatorcontrib>ZHANG LIN</creatorcontrib><creatorcontrib>FAN JUNHUA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BURROWS FRANCIS J</au><au>FRITZ LAWRENCE C</au><au>LE BRAZIDEC JEAN-YVES</au><au>BOEHM MARCUS F</au><au>MCHUGH SEAN K</au><au>ZHANG LIN</au><au>FAN JUNHUA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Ansamycins having improved pharmacological and biological properties</title><date>2005-12-01</date><risdate>2005</risdate><abstract>Ansamycins and methods of preparing and using the same are described. At least some of these ansamycins exhibit one or more of improved aqueous formulation ability, chemical stability, and bioavailability. Some of the derivatives described are dimers. These and others described can include one or more solubilizing groups that have expected merit in rendering the overall compounds useful as drugs and prodrugs.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_epo_espacenet_US2005267122A1 |
source | esp@cenet |
subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Ansamycins having improved pharmacological and biological properties |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T05%3A36%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BURROWS%20FRANCIS%20J&rft.date=2005-12-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2005267122A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |