Regioselective hydroxylation, functionalisation and protection of spirolactams

Regioselective hydroxylation, functionalisation and protection of spirolactams

The invention provides highly functionalised spiro-fused azetidinones having a cyclohexane moiety with the desired number of protected or unprotected hydroxyl groups which are introduced with high stereo and regioselectivity, as well as processes for obtaining the compounds.

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Bibliographische Detailangaben
Hauptverfasser: MARIN PEDRO N, CANTERO NURIA T, QUINTANA SERGIO M, BERNABE PAJARES MANUEL
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention provides highly functionalised spiro-fused azetidinones having a cyclohexane moiety with the desired number of protected or unprotected hydroxyl groups which are introduced with high stereo and regioselectivity, as well as processes for obtaining the compounds.