Immunomodulatory compounds

The present invention relates to novel heterocyclic compounds, to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HUXLEY PHILIP, COULTER THOMAS S, BRENNAN CHRIS J, UDDIN MUHAMMED K, THRIGE DORTHE D.G, GHIRON CHIARA, GORAN PETTERSSON LARS O, MATTHEWS IAN R
Format:	Patent
Sprache:	eng
Schlagworte:	CHECKING-DEVICES CHEMISTRY HANDLING OF COINS OR OF PAPER CURRENCY OR SIMILAR VALUABLEPAPERS, e.g. TESTING, SORTING BY DENOMINATIONS, COUNTING,DISPENSING, CHANGING OR DEPOSITING HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel heterocyclic compounds, to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28.