Water soluble nanoparticles and method for their production

Hydrophilic dispersions of stable nano-sized particles are provided comprising: (a) a water-insoluble or water-soluble active compound, wherein said active compound is selected from the group consisting of a macrolide antibiotic, donepezil hydrochloride, an azole compound and a taxane; and (b) an am...

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Bibliographische Detailangaben
Hauptverfasser: STERN ERWIN, ZELKIND ILYA, KOPYLOV MICHAEL, RATNER GALINA, TULBOVICH BORIS, GOLDSHTEIN VADIM, SKYLARSKY OLGA, GOLDSHTEIN RINA, KAMBURG ROMAN
Format: Patent
Sprache:eng
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Zusammenfassung:Hydrophilic dispersions of stable nano-sized particles are provided comprising: (a) a water-insoluble or water-soluble active compound, wherein said active compound is selected from the group consisting of a macrolide antibiotic, donepezil hydrochloride, an azole compound and a taxane; and (b) an amphiphilic polymer which wraps said active compound in a non-crystalline manner to form a nano-sized molecular entity in which no valent bonds are formed.