Compositions and their uses directed to cell growth and maintenance proteins

Antisense compounds, compositions and methods are provided for modulating the expression of G protein-coupled receptor kinase 6. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding G protein-coupled receptor kinase 6. Methods of...

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Hauptverfasser: FREIER SUSAN M, CHIANG MING-YI, WARD DONNA T, DEAN NICHOLAS M, POPOFF IAN, MONIA BRETT P, DOBIE KENNETH W, BENNETT C. F, JAIN RAVI
Format: Patent
Sprache:eng
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Zusammenfassung:Antisense compounds, compositions and methods are provided for modulating the expression of G protein-coupled receptor kinase 6. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding G protein-coupled receptor kinase 6. Methods of using these compounds for modulation of G protein-coupled receptor kinase 6 expression and for treatment of diseases associated with expression of G protein-coupled receptor kinase 6 are provided.