Method for screening a substance which can suppress degradation of a nuclear receptor or a substance which can promote degradation of a nuclear receptor

A method is provided for screening a substance which can suppress or promote degradation of a nuclear receptor, comprising the steps of: judging whether or not a test substance can suppress or promote binding of a CHIP with a nuclear receptor via a chaperone protein; and screening a test substance w...

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Hauptverfasser: TATEISHI YUKIYO, YANAGISAWA JUNN
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creator TATEISHI YUKIYO
YANAGISAWA JUNN
description A method is provided for screening a substance which can suppress or promote degradation of a nuclear receptor, comprising the steps of: judging whether or not a test substance can suppress or promote binding of a CHIP with a nuclear receptor via a chaperone protein; and screening a test substance which can suppress the binding as a substance which can suppress degradation of a nuclear receptor or screening a test substance which can promote the binding as a substance which can promote degradation of a nuclear receptor.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
title Method for screening a substance which can suppress degradation of a nuclear receptor or a substance which can promote degradation of a nuclear receptor
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