Method for screening a substance which can suppress degradation of a nuclear receptor or a substance which can promote degradation of a nuclear receptor

A method is provided for screening a substance which can suppress or promote degradation of a nuclear receptor, comprising the steps of: judging whether or not a test substance can suppress or promote binding of a CHIP with a nuclear receptor via a chaperone protein; and screening a test substance w...

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Bibliographische Detailangaben
Hauptverfasser:	TATEISHI YUKIYO, YANAGISAWA JUNN
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method is provided for screening a substance which can suppress or promote degradation of a nuclear receptor, comprising the steps of: judging whether or not a test substance can suppress or promote binding of a CHIP with a nuclear receptor via a chaperone protein; and screening a test substance which can suppress the binding as a substance which can suppress degradation of a nuclear receptor or screening a test substance which can promote the binding as a substance which can promote degradation of a nuclear receptor.