Genes

The invention relates to mutations in B-Raf gene products. The mutations described are identified in human tumours of natural origin. These mutations are associated with cancerous phenotypes and can be used as a basis for the diagnosis of cancer, cancerous cells or a predisposition to cancer in huma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MARSHALL CHRIS, MARAIS RICHARD M, FUTREAL ANDY, STRATTON MIKE, WOOSTER RICHARD
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to mutations in B-Raf gene products. The mutations described are identified in human tumours of natural origin. These mutations are associated with cancerous phenotypes and can be used as a basis for the diagnosis of cancer, cancerous cells or a predisposition to cancer in human subjects, and the development of anti-cancer therapeutics.