Thienodibenzoazulene compounds as tumor necrosis factor inhibitors

The present invention relates to the dibenzoazulene compounds represented by formula I as well as to their pharmaceutical preparations for the inhibition of tumor necrosis factor alpha (TNF-alpha) and interleukine 1 (IL-1) in mammals at all diseases and conditions where these mediators are excessive...

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Bibliographische Detailangaben
Hauptverfasser: ZUPANOVIC ZELJKO, MERCEP MLADEN, MESIC MILAN, PESIC DIJANA, HRVACIC BOSKA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to the dibenzoazulene compounds represented by formula I as well as to their pharmaceutical preparations for the inhibition of tumor necrosis factor alpha (TNF-alpha) and interleukine 1 (IL-1) in mammals at all diseases and conditions where these mediators are excessively secreted. The compounds of the present invention also demonstrate an analgetic action and can be used to relieve pain.