Tissue preservation assembly and method of making and using the same

A sterilized device for storing and transferring a tissue sample collected in a sterile field is provided having a hermetically sealed package containing a tissue storage chamber sealed with a removable cap creating a sample storage chamber housing a tissue preservation agent. The package may be provided as a lid sealed to a tray, a plastic bag that is sealed, or two pieces of plastic sealed along the edges. An interior compartment is created within the package, which is sterile along with the sample container and its contents. A tissue preservation agent is provided to stabilized RNA in a tissue sample. The sterilized device is intended for use in storing and transferring a tissue sample from a patient while in a sterile field. The sterilized device is a single assembly that eliminates disrupting a sterile field in an operating room and transferring an exposed tissue sample out of the sterile field.