Process for the asymmetric synthesis of dihydrobenzoxathins

This invention relates to an asymmetric synthesis of sulfides via a chiral sulfoxide directed stereospecific reduction of alpha,beta-unsaturated sulfoxide to the saturated sulfide. These sulfides can be useful as selective estrogen receptor modulators or anti-neoplastic agents.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SONG ZHIGUO J, WATERS MARJORIE S
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:This invention relates to an asymmetric synthesis of sulfides via a chiral sulfoxide directed stereospecific reduction of alpha,beta-unsaturated sulfoxide to the saturated sulfide. These sulfides can be useful as selective estrogen receptor modulators or anti-neoplastic agents.