Benzopyran compounds useful for treating inflammatory conditions

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R 2, R3, and R4 are as described in th...

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Hauptverfasser:	FLETCHER THERESA, KIEFER JAMES, SPRINGER JOHN, DEPROW ANGELA M, HAMPER BRUCE, MCCALL JOHN, TALLEY JOHN, KRAMER STEVEN, LUDWIG CINDY, LAIO SUBO, KOSZYK FRANCIS, LIMBURG DAVID, BROWN DAVID, CARTER JEFFERY, HUFF RENEE, YU YI, HALLINAN E. A, WANG LIJUAN, ASTON KARL, XING LI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R 2, R3, and R4 are as described in the specification.