Composition for treating inflammatory bowel disease

A method for reducing inflammation in inflammatory bowel disease is disclosed. The method comprises reducing the expression of endothelial cell adhesion molecules in the vasculature of the bowel wall by administering a therapeutic dosage of an effective amount of a blend of vitamin E TPGS and gamma-...

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Bibliographische Detailangaben
Hauptverfasser: ALEXANDER J. S, PAPAS KONSTANTINOS A, PAPAS ANDREAS M
Format: Patent
Sprache:eng
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Zusammenfassung:A method for reducing inflammation in inflammatory bowel disease is disclosed. The method comprises reducing the expression of endothelial cell adhesion molecules in the vasculature of the bowel wall by administering a therapeutic dosage of an effective amount of a blend of vitamin E TPGS and gamma-tocopherol. Gamma-tocopherol is also useful when used alone in the invention. The reduction in endothelial cell adhesion molecules is due to the deactivation of endothelial NFkappa-B by the composition.