Benzamidine derivatives and process for production thereof

A process for production of an amidine derivative represented by the following Formula (II) [wherein, R represents a hydrogen atom, an unsubstituted or substituted phenyl group, an unsubstituted or substituted C1-C10 alkyl group, an unsubstituted or substituted C1-C10 alkoxy group, an unsubstituted...

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Hauptverfasser: TABE MASAYASU, HARA TAKAYUKI, MINOSHIMA TORU
Format: Patent
Sprache:eng
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Zusammenfassung:A process for production of an amidine derivative represented by the following Formula (II) [wherein, R represents a hydrogen atom, an unsubstituted or substituted phenyl group, an unsubstituted or substituted C1-C10 alkyl group, an unsubstituted or substituted C1-C10 alkoxy group, an unsubstituted or substituted C1-C10 alkoxycarbonyl group, or a hydroxyl group present at the ortho, meta, or para position] or a salt thereof, comprising the steps of reducing an amidoxime derivative represented by the following Formula (I) [wherein, R represents a hydrogen atom, an unsubstituted or substituted phenyl group, an unsubstituted or substituted C1-C10 alkyl group, an unsubstituted or substituted C1-C10 alkoxy group, an unsubstituted or substituted C1-C10 alkoxycarbonyl group, or a hydroxyl group present at the ortho, meta, or para position] with zinc in an acetic acid as a solvent.