Compounds useful as A3 adenosine receptor agonists

Adenosine analogue-type A3 receptor agonists having an N6 nitrogen substituted by a group which is usually -CH2-CYCLE, where CYCLE is a specified heteroaromatic group, particularly a pyrridyl or a bicyclic group, for example benzoxazole. Preferred CYCLE moieties are substituted in specified position...

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Bibliographische Detailangaben
Hauptverfasser:	DAVIES ROBIN H, SEVILLANO LUIS G, MCGUIGAN CHRISTOPHER
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
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Beschreibung
Zusammenfassung:	Adenosine analogue-type A3 receptor agonists having an N6 nitrogen substituted by a group which is usually -CH2-CYCLE, where CYCLE is a specified heteroaromatic group, particularly a pyrridyl or a bicyclic group, for example benzoxazole. Preferred CYCLE moieties are substituted in specified positions by, in particular, halo or methyl and, at another position, a dialkylamine.