Branched polyalkylene glycols

The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal amino group or the C-terminal carboxyl group in a polypeptide or a group convertible into the group having...

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Bibliographische Detailangaben
Hauptverfasser: MAKAI MAYUMI, YAMASAKI MOTOO, MURAKAMI TATSUYA, KUWABARA TAKASHI, SUZAWA TOSHIYUKI, SAKURAI NORIKO, YAMASHITA KINYA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal amino group or the C-terminal carboxyl group in a polypeptide or a group convertible into the group having reactivity are bound; and a physiologically active polypeptide modified with the branched polyalkylene glycol.