Stabiliser for radiopharmaceuticals

The present invention provides an improved stabiliser for radiopharmaceuticals which inhibits impurities from being produced by two kinds of decomposition mechanisms and exhibits such an effect that the shelf life of a radiopharmaceutical after its preparation is prolonged as compared with conventio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HANAOKA KOICHI, STOREY ANTHONY E, BRAUERS GEORG, MINOSAKO YOSHIHITO, HOMMA KOICHI, SHIRAKAMI YOSHIFUMI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides an improved stabiliser for radiopharmaceuticals which inhibits impurities from being produced by two kinds of decomposition mechanisms and exhibits such an effect that the shelf life of a radiopharmaceutical after its preparation is prolonged as compared with conventional ones. The improvement comprises a combination of an amino-substituted aromatic carboxylic acid or its salt, ester or amide in combination with a diphosphonic acid or its salt.