Substituted quinazolinone compounds

A variety of small molecule, guanidine-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structure IA, IB, and IC where the values of the variables are defined here...

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Bibliographische Detailangaben
Hauptverfasser:	MUSSO DAVID L, CONLEE CHRISTOPHER R, CHU DANIEL, THOMPSON BRIAN D, CHAUDER BRIAN A, SMITH AARON, BISHOP MICHAEL J, SWAIN WILLIAM R, AURRECOECHEA NATALIA, KUNTZ JUDITH DE ARMAS, SPEAKE JASON D, THOMSON STEPHEN A, DU KIEN S, BOYCE RUSTUM S, BARVIAN KEVIN K
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A variety of small molecule, guanidine-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structure IA, IB, and IC where the values of the variables are defined herein.