4-Cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists
Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury...
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| creator | YOUNG STEVEN D MUNSON PETER WHITTER WILLIE SANDERSON PHILIP E PHILLIPS BRIAN T MCCAULEY JOHN A THOMPSON WAYNE BUTCHER JOHN DIECKHAUS CHRISTINE MCINTYRE CHARLES J LIVERTON NIGEL LAYTON MARK E |
| description | Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | 4-Cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists |
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