4-Cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists

4-Cycloalkylaminopyrazolo pyrimidine NMDA/NR2B antagonists

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury...

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Bibliographische Detailangaben
Hauptverfasser: YOUNG STEVEN D, MUNSON PETER, WHITTER WILLIE, SANDERSON PHILIP E, PHILLIPS BRIAN T, MCCAULEY JOHN A, THOMPSON WAYNE, BUTCHER JOHN, DIECKHAUS CHRISTINE, MCINTYRE CHARLES J, LIVERTON NIGEL, LAYTON MARK E
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.