Process for forming amorphous atorvastatin

Forming amorphous atorvastatin comprises the steps of dissolving atorvastatin in a hydroxylic solvent, followed by rapidly evaporating the solvent. In another aspect, a composition comprises particles of amorphous atorvastatin and a core.

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Bibliographische Detailangaben
Hauptverfasser: WATERMAN KENNETH CRAIG, LORENZ DOUGLAS A
Format: Patent
Sprache:eng
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Zusammenfassung:Forming amorphous atorvastatin comprises the steps of dissolving atorvastatin in a hydroxylic solvent, followed by rapidly evaporating the solvent. In another aspect, a composition comprises particles of amorphous atorvastatin and a core.