Testis-specific receptor

Novel receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise an extracellular domain of a cell-surface receptor that is expressed in testis cells. The polypeptides may be used within methods for detecting ligand...

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Hauptverfasser: FARRAH THERESA M, O'HARA PATRICK J, FOSTER DONALD C, GRANT FRANK J, BAUMGARTNER JAMES W
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Novel receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise an extracellular domain of a cell-surface receptor that is expressed in testis cells. The polypeptides may be used within methods for detecting ligands that promote the proliferation and/or differentiation of testis cells, and may also be used in the development of male-specific contraceptives and infertility treatments.