Automatic eukaryotic artificial chromosome vector

The present invention is directed to novel recombinant nucleic acids for introducing yeast chromosomal elements into the genomes of bacteria. The invention provides methods to convert the modified bacterial genomes into artificial yeast chromosomes by fusing the bacteria with yeast that linearize th...

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Bibliographische Detailangaben
Hauptverfasser: HITZEMAN RONALD A, CHISHOLM GEORGE E
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to novel recombinant nucleic acids for introducing yeast chromosomal elements into the genomes of bacteria. The invention provides methods to convert the modified bacterial genomes into artificial yeast chromosomes by fusing the bacteria with yeast that linearize the modified bacterial genomes, to produce artificial chromosomes.