Thiophenylthiopyrane dioxides as mmp or tnf-alpha inhibitors

A compound of the formula: in which R is optionally substituted phenyl, optionally substituted naphthyl, optionally substituted bicyclic heterocyclic group, optionally substituted lower alkenyl or optionally substituted lower alkynyl, and R is carboxy or protected carboxy, or a salt thereof, useful...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MIZUTANI TSUYOSHI, SAWADA AKIHIKO, OHNE KAZUHIKO, NEYA MASAHIRO, ISHIBASHI NAOKI, ABE YOSHITO, INOUE MAKOTO
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A compound of the formula: in which R is optionally substituted phenyl, optionally substituted naphthyl, optionally substituted bicyclic heterocyclic group, optionally substituted lower alkenyl or optionally substituted lower alkynyl, and R is carboxy or protected carboxy, or a salt thereof, useful for treating and/or preventing MMP- or TNF-alpha mediated diseases.