Stabilization of t4 endonuclease v

The invention provides T4 endonuclease V compositions that exhibit enhanced stability, including stability at non-refrgerated temperatures, through reduced activity of cryptic proteases. Methods for detecting cryptic protease activity and methods for reducing such activity are also provided.

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Bibliographische Detailangaben
Hauptverfasser: YAROSH DANIEL B, BROWN ANNE B, BROWN DAVID A
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides T4 endonuclease V compositions that exhibit enhanced stability, including stability at non-refrgerated temperatures, through reduced activity of cryptic proteases. Methods for detecting cryptic protease activity and methods for reducing such activity are also provided.