Amino nicotinate derivatives as glucokinase (GLK) modulators

The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R , R , R , n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	JONES CLIFFORD DAVID, MCKERRECHER DARREN, GASKIN HAROLD, JAMES ROGER, HAYTER BARRY RAYMOND, HARGREAVES RODNEY BRIAN, ALLEN JOANNE VICTORIA, JOHNSTONE CRAIG, CURRIE GORDON STUART, CAULKETT PETER WILLIAM RODNEY
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R , R , R , n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase.