Methods and apparatus for characterization of tissue samples

The invention provides methods for determining the probability that a given region of a tissue sample contains tissue of a given category, such as CIN 1 (cervical intraepithelial neoplasia, grade 1), CIN 2/3 (cervical intraepithelial neoplasia grades 2 and/or 3), normal squamous, normal columnar, an...

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Bibliographische Detailangaben
Hauptverfasser: DRAAYER BRET F, SUM STEPHEN T, FLEWELLING ROSS F, SCHOTT JEAN-PIERRE, COSTA PETER J, SCHOMACKER KEVIN T
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides methods for determining the probability that a given region of a tissue sample contains tissue of a given category, such as CIN 1 (cervical intraepithelial neoplasia, grade 1), CIN 2/3 (cervical intraepithelial neoplasia grades 2 and/or 3), normal squamous, normal columnar, and metaplasia, for example. The invention provides increased diagnostic accuracy by combining a plurality of statistical classification techniques. Furthermore, in one embodiment, the invention comprises combining one or more statistical techniques with one or more non-statistical classification techniques.