Modified proteinase inhibitors

Modified proteinase inhibitors having enhanced inhibition efficacy when compared to the naturally occurring counterparts. Also provided are polynucleotide molecules encoding the modified proteinase inhibitors, vectors and other recombinant nucleic acid constructs, transgenic cells, and transgenic or...

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Bibliographische Detailangaben
Hauptverfasser:	MCPHERSON MICHAEL JOHN, URWIN PETER EDWARD, ATKINSON HOWARD JOHN
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS NEW PLANTS OR PROCESSES FOR OBTAINING THEM ORGANIC CHEMISTRY PEPTIDES PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Modified proteinase inhibitors having enhanced inhibition efficacy when compared to the naturally occurring counterparts. Also provided are polynucleotide molecules encoding the modified proteinase inhibitors, vectors and other recombinant nucleic acid constructs, transgenic cells, and transgenic organisms that comprise the polynucleotide molecules. Further disclosed are methods for producing the modified proteinase inhibitors, and methods and compositions for increasing the resistance of a cell or an organism to proteolytic damages, particularly the damages caused by a pest or a pathogen.