Alpha-glucosidase inhibitors and their synthesis from a natural source

The present invention provides novel alpha-glucosidase inhibitory compound (-)-mesquitol and its analogs isolated in significant yield from traditional medicinal plant Dichrostachys cinerea and further modification of (-)-mesquitol to enhance the alpha- glucosidase inhibitory potential; the inventio...

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Hauptverfasser: RAGHAVAN KONDAPURAM VIJAYA, RAO RAO JAGADEESHWAR, YADAV JHILLUSINGH, KUMAR UPPARAPALLI SAMPATH, REDDY SINGIREDDY VENKAT, RAO JANASWAMY MADHUSUDANA, TIWARI ASHOK KUMAR
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides novel alpha-glucosidase inhibitory compound (-)-mesquitol and its analogs isolated in significant yield from traditional medicinal plant Dichrostachys cinerea and further modification of (-)-mesquitol to enhance the alpha- glucosidase inhibitory potential; the invention also identifies the usage of (-)-mesquitol and its analogues, based on their alpha-glucosidase inhibitory activity, as broad based potential therapeutics as antihyperglycernic, antidiabatic, antiobesity, antiviral, anticancer, immunestimulants and the like.