Substituted biphenyl compounds for the treatment of inflammation

Substituted biphenyl compounds for the treatment of inflammation

A class of substituted biphenyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula III: wherein each of R through R is independently selected from hydrido, halo, lower alkoxy, lower haloalkyl, amino, low...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LI JAMES J, NORTON MONICA B, REITZ DAVID B
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A class of substituted biphenyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula III: wherein each of R through R is independently selected from hydrido, halo, lower alkoxy, lower haloalkyl, amino, lower alkylamino, lower dialkylamino, and lower haloalkoxy; or wherein R and R together form -O(CH2)nO-; wherein n is 1-2, inclusive; or a pharmaceutically-acceptable salt thereof.