Pharmaceutical compositions containing an effervescent acid-base couple

A pharmaceutical composition in the form of effervescent tablets comprising an active ingredient and an effervescent blend, comprising an acidic component and sodium glycine carbonate as alkaline components. Preferred acid components are fumaric acid, maleic acid, and their salts. Tablets are prepar...

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Hauptverfasser: BRAMBILLA GAETANO, MEZZADRI ROSA, VENTURA PAOLO, ACERBI DANIELA, CHIESI PAOLO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A pharmaceutical composition in the form of effervescent tablets comprising an active ingredient and an effervescent blend, comprising an acidic component and sodium glycine carbonate as alkaline components. Preferred acid components are fumaric acid, maleic acid, and their salts. Tablets are prepared in normal thermohygrometric conditions and with standard tabletting equipment. A pre-granulation process is also disclosed.