Genetic test for the identification of carriers of complex vertebral malformations in cattle

Genetic markets for identifying bovine carriers of complex vertebral malformation (CVM) disease gene are described. The genetic markers, including the microsatellite markers BM4129, INRAA003, BMS2790, ILSTS029, INRA123, BM220, HUJ246, BMS862, BMS937, BL1048, BMS2095 and BMS1266 and the bovine SLC35A...

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Hauptverfasser: THOMSEN BO, JEPPESEN METTE, SVENDSEN SOREN, AASBERG ANDERS, JONKER MARCK, PANITZ FRANK, JENSEN HELLE, HOJ ANETTE, HORN PER, BENDIXEN CHRISTIAN, HOLM LARS-ERIK, NIELSEN VIVI HUNNICKE
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Sprache:eng
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Zusammenfassung:Genetic markets for identifying bovine carriers of complex vertebral malformation (CVM) disease gene are described. The genetic markers, including the microsatellite markers BM4129, INRAA003, BMS2790, ILSTS029, INRA123, BM220, HUJ246, BMS862, BMS937, BL1048, BMS2095 and BMS1266 and the bovine SLC35A3 gene, are located on bovine chromosome BTA3. The G/T polymorphism at position 559 of the bovine SLC35A3 gene is identified as being causative and diagnostic for CVM in cattle.