Deep gradient-density filter device

The present invention provides a deep gradient-density filter device capable of effectively filtering a fluid containing a distribution of particles in the range of approximately 25 microns to approximately 0.2 micron at a fluid velocity of at least approximately 100 cm/hr and an initial hydraulic p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ROYCE JONATHAN, RAMAN VEN ANANTHA, YAVORSKY DAVID P, TOMASKO MATTHEW ALEXANDER
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a deep gradient-density filter device capable of effectively filtering a fluid containing a distribution of particles in the range of approximately 25 microns to approximately 0.2 micron at a fluid velocity of at least approximately 100 cm/hr and an initial hydraulic permeability of greater than approximately 10 cm/hr/psi. The deep gradient-density filter device comprises several layers of filtration material, each having specific predetermined particle retention properties. In one product embodiment of the present invention, the deep gradient-density filter device uses "loose" fibrillated cellulose fiber material as a primary filter element. In a method aspect of the invention, the deep gradient-density filter device is used for either the secondary clarification of industrial-scale cultured or fermented protein-containing biopharmaceutical fluids or the primary clarification of pilot-scale volumes of said fluids.