Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polyn...

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Hauptverfasser:	CHAPOVAL ANDREI, JI WEIZHEN, BURGESS CATHERINE E, SHIMKETS RICHARD A, LI LI, SHENOY SURESH G, STONE DAVID J, EDINGER SHLOMIT R, KEKUDA RAMESH, ZHONG MEI, ALVAREZ ENRIQUE, RASTELLI LUCA, EISEN ANDREW, SMITHSON GLENNDA, CASMAN STACIE J, RIEGER DANIEL K, MISHRA VISHNU, DHANABAL MOHANRAJ, TWOMLOW NANCY, MEZES PETER S, ZERHUSEN BRYAN D, ETTENBERG SETH, MAZUR ANN, GERLACH VALERIE, PATTURAJAN MEERA, KHRAMTSOV NIKOLAI V, ALSOBROOK JOHN P, PENA CAROL E. A, SPADERNA STEVEN K, PEYMAN JOHN A, TCHERNEV VELIZAR T, VERNET CORINE A.M, GROSSE WILLIAM M, STARLING GARY, BOLDOG FERENC L, VOSS EDWARD Z, MILLET ISABELLE, GANGOLLI ESHA A, MCQUEENEY KELLY, GORMAN LINDA, ROTHENBERG MARK E, SPYTEK KIMBERLY A, LEPLEY DENISE M, BARON MELANIE, HACKETT CRAIG, ANDERSON DAVID W, MALYANKAR URIEL M, ELLERMAN KAREN, GUO XIAOJIA (SASHA), MACDOUGALL JOHN R, MILLER CHARLES E, PADIGARU MURALIDHARA
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.