Morpholin-acetamide derivatives for the treatment of inflammatory diseases

Compounds of formula (I) wherein: R represents C1-16 alkyl, C2-6alkenyl, C2-6alkynyl, C2-6alkynyl-Y -, aryl-Y -, heteroaryl-Y -, aryl-(O)t-aryl-Y -, aryl-(O)t-heteroaryl-Y -, heteroaryl-(O)t-aryl-Y -, heteroaryl-(O)t-heteroaryl-Y -, C2-6 alkenyl-Y -, aryl-O-Y -, heteroaryl-O-Y -, C1-16 alkyl-SO2-Y -...

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Bibliographische Detailangaben
Hauptverfasser:	ANCLIFF RACHAEL ANNE, HARRISON LEE ANDREW, KEELING SUZANNE ELAINE, HODGSON SIMON TEANBY, COOK CAROLINE MARY, ELDRED COLIN DAVID, GORE PAUL MARTIN, LEWELL XIAO QING, JUDD DUNCAN BRUCE, ROBERTSON GRAEME MICHAEL, SWANSON STEPHEN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of formula (I) wherein: R represents C1-16 alkyl, C2-6alkenyl, C2-6alkynyl, C2-6alkynyl-Y -, aryl-Y -, heteroaryl-Y -, aryl-(O)t-aryl-Y -, aryl-(O)t-heteroaryl-Y -, heteroaryl-(O)t-aryl-Y -, heteroaryl-(O)t-heteroaryl-Y -, C2-6 alkenyl-Y -, aryl-O-Y -, heteroaryl-O-Y -, C1-16 alkyl-SO2-Y -,M-Y -,J -Y -, -CN or C3-8 cycloalkyl-Y - or C3-8 cycloalkenyl-Y -, which cycloalkyl or cycloalkenyl may be optionally substituted by one or more hydroxyl or C1-16 Alkyl groups; R represents hydrogen or C1-16 alkyl; X represents ethylene or a group of formula CRR wherein R and R independently represent hydrogen or Calkyl or R and R may together with the carbon atom to which they are attached form a C3-8 cycloalkyl group; R and R independently represent hydrogen or C1-14 alkyl; Z represents a bond, CO, SO2, CR R (CH2)n, (CH2)nCR R , CHR (CH2)nO, CHR (CH2)nS, CHR (CH2)nOCO, CHR (CH2