Oligolysine transducing domain, oligolysine-cargo molecule complex and uses thereof

This invention relates to delivery of biologically active organic molecules e.g. peptides or proteins into the cytoplasm. In this invention, transducing domain which is covalently attached to organic molecules is oligolysine which comprise 3-12 lysine residues. The oligolysine transducing domain-bin...

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Bibliographische Detailangaben
Hauptverfasser: WON MOO-HO, HAN KYU-HYUNG, LEE KIL-SOO, KANG TAEUN, PARK JINSEU, CHOI SOO-YOUNG, KANG JUNG-HOON, KWON HYEOK-YIL
Format: Patent
Sprache:eng
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Zusammenfassung:This invention relates to delivery of biologically active organic molecules e.g. peptides or proteins into the cytoplasm. In this invention, transducing domain which is covalently attached to organic molecules is oligolysine which comprise 3-12 lysine residues. The oligolysine transducing domain-binding fusion protein is efficiently transducible into cytoplasm, and biologically active.