Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof

The present invention provides epitopes present on cancer cells and important in physiological phenomena such as cell rolling, metastasis, and inflammation. Therapeutic and diagnostic methods and compositions using antibodies capable of binding to the epitopes are provided. Methods and compositions...

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Hauptverfasser: SZANTHON ESTER, LAZAROVITS JANETTE, HAGAY YOCHEVED, NIMROD ABRAHAM, RICHTER TAMAR, PLAKSIN DANIEL, VOGEL TIKVA, PERETZ TUVIA, COOPERMAN LENA, MAR-HAM HAGIT, AMIT BOAZ, LEVANON AVIGDOR
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides epitopes present on cancer cells and important in physiological phenomena such as cell rolling, metastasis, and inflammation. Therapeutic and diagnostic methods and compositions using antibodies capable of binding to the epitopes are provided. Methods and compositions according to the present invention can be used in diagnosis of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease