Beads having identifiable Raman markers

This invention comprises novel enhancing particle structures and beads which can have receptor molecules attached thereto. The structures are useful for Raman spectroscopic detection of markers associated with analyses of analytes in complex solutions containing molecules of interest. Analytes that...

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Bibliographische Detailangaben
Hauptverfasser: YEVIN OLEG A, GINZBURG LEV, NUFERT THOMAS H, KREIMER DAVID I
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention comprises novel enhancing particle structures and beads which can have receptor molecules attached thereto. The structures are useful for Raman spectroscopic detection of markers associated with analyses of analytes in complex solutions containing molecules of interest. Analytes that can be detected using these methods include nucleic acids, proteins, cytokines, hormones, vitamins, those from bacteria, viruses, cells and tissues, and other molecules that can specifically bind to the analyte receptors. Beads can be used as biomarkers, as analytical tools, and as tags for combinatorial syntheses.