Structural basis of quorum sensing signal generation and methods and therapeutic agents derived therefrom

The three dimensional structure of acyl-homoserine lactone synthases, and particularly EsaI and LasI, and uses thereof. Novel acyl-homoserine lactone synthases from mycobacteria, nucleic acid molecules encoding such synthases, recombinant molecules and host cells, and uses thereof.

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Bibliographische Detailangaben
Hauptverfasser:	SCHWEIZER HERBERT P, HOANG TUNG THANH, CHURCHILL MAIR E.A, MURPHY FRANK V, GOULD TY A, VON BODMAN SUSANNE B, WATSON WILLIAM T
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The three dimensional structure of acyl-homoserine lactone synthases, and particularly EsaI and LasI, and uses thereof. Novel acyl-homoserine lactone synthases from mycobacteria, nucleic acid molecules encoding such synthases, recombinant molecules and host cells, and uses thereof.