Substituted cyclic amine metalloprotease inhibitors

Substituted cyclic amine metalloprotease inhibitors

The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I). Also disclose...

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Hauptverfasser: CHENG MENYAN, BOOKLAND ROGER GUNNARD, NATCHUS MICHAEL GEORGE, TAIWO YETUNDE OLABISI, PIKUL STANISLAW, DE BISWANATH, ALMSTEAD NEIL GREGORY
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Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator CHENG MENYAN
BOOKLAND ROGER GUNNARD
NATCHUS MICHAEL GEORGE
TAIWO YETUNDE OLABISI
PIKUL STANISLAW
DE BISWANATH
ALMSTEAD NEIL GREGORY
description The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I). Also disclosed are compounds, pharmaceutical compositions and methods of treating diseases characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Substituted cyclic amine metalloprotease inhibitors
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