Substituted cyclic amine metalloprotease inhibitors

The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I). Also disclose...

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Bibliographische Detailangaben
Hauptverfasser: CHENG MENYAN, BOOKLAND ROGER GUNNARD, NATCHUS MICHAEL GEORGE, TAIWO YETUNDE OLABISI, PIKUL STANISLAW, DE BISWANATH, ALMSTEAD NEIL GREGORY
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I). Also disclosed are compounds, pharmaceutical compositions and methods of treating diseases characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.