6-5, 6-6, or 6-7 Heterobicycles as factor xa inhibitors

The present application describes 6-5, 6-6, or 6-7 heterobicycles of Formula I or pharmaceutically acceptable salt forms thereof: wherein ring P is a 6-membered heteroaromatic and ring M is a 5-, 6-, or 7-membered non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful...

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1. Verfasser: PINTO DONALD JOSEPH PHILLIP
Format: Patent
Sprache:eng
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Zusammenfassung:The present application describes 6-5, 6-6, or 6-7 heterobicycles of Formula I or pharmaceutically acceptable salt forms thereof: wherein ring P is a 6-membered heteroaromatic and ring M is a 5-, 6-, or 7-membered non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.