Method for monitoring nucleic acid assays using synthetic internal controls with reversed nucleotide sequences

The present invention relates to methods and compositions that provide a positive control to identify inhibition during a signal amplification reaction. The methods and compositions of the present invention are designed to run in the same tube or assay environment as the experimental or target sampl...

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Bibliographische Detailangaben
Hauptverfasser: WALKERPEACH CINDY R, DUBOIS DWIGHT B
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to methods and compositions that provide a positive control to identify inhibition during a signal amplification reaction. The methods and compositions of the present invention are designed to run in the same tube or assay environment as the experimental or target sample and contain a copy of the target sequence in an inverted form.