Use of generic oligonucleotide microchips to detect protein-nucleic acid interactions

Nucleic acids or proteins immobilized in a gel pad are interacting with a protein and the nucleic acid-protein and protein-protein interactions are characterized and measured. Large-scale, parallel measurements of these interactions can be examined to provide a powerful tool in elucidating interacti...

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Hauptverfasser: ZASEDATELEVA OLGA A, MIRZABEKOV ANDREI, PROKOPENKO DMITRY V, KRYLOV ALEXANDER S
Format: Patent
Sprache:eng
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Zusammenfassung:Nucleic acids or proteins immobilized in a gel pad are interacting with a protein and the nucleic acid-protein and protein-protein interactions are characterized and measured. Large-scale, parallel measurements of these interactions can be examined to provide a powerful tool in elucidating interactions between proteins and nucleic acids.