Sampling article for determining quantitative and qualitative drug transfer to skin

An article for measuring external drug transfer to skin surfaces includes a high molecular weight polyolefin substrate film and a skin-adhering element attached to the polyolefin substrate film. The substrate film has a texture that simulates skin roughness and topography on the surface facing a dru...

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Bibliographische Detailangaben
Hauptverfasser:	WORKMAN JEROME JAMES, ADLER TERRY WILLIAM, CUNNINGHAM COREY THOMAS
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DIAGNOSIS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE IDENTIFICATION INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEASURING MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SURGERY TESTING
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Beschreibung
Zusammenfassung:	An article for measuring external drug transfer to skin surfaces includes a high molecular weight polyolefin substrate film and a skin-adhering element attached to the polyolefin substrate film. The substrate film has a texture that simulates skin roughness and topography on the surface facing a drug delivery medium. The substrate film, skin-adhering element, and all other components of, or in contact with, the sampling article provide minimum interference with chemical analysis of the active drug being measured.